Ninety-five genotypes of Physalis spp. were evaluated in Morelos, Mexico, in order to find genotypes with genetic tolerance to the disease caused by Fusarium sp. It was evaluated the percent of disease plants four times (23, 36, 49 and 62 days after the trasplant) and the fruit yield. The statistics analysis consisted in variance analysis, means comparation and main components analysis. The genotypes 17GRO01, 48JAL08, 51JAL09, 58GRO06, 63JAL15, 77MEX04, 82MEX06, 85JAL24, 106MOR02 and SJ/27(1) were the most tolerant to Fusarium sp.; 94, 57, 61, 92, 93 and 30 genotypes were resistant to the disease, with good yield and big fruits (genotypes desirable for breeding programs); 77MEX04, 82MEX06, 58GRO06, 106MOR02 and SJ/27(1) genotypes were the most productive, while 77MEX04, 82MEX06 and SJ/27(1) were the most tolerant to Fusarium sp.