With the purpose of studying the dynamics of dry matter (DM) and N, P, and K accumulation in potato cv. Alpha, we established three experiments in farmers’ fields during the spring-summer (SS) and autumn-winter (AW) growth cycles. Soils in this study were fertilized to prevent any limitation of nutrients. Fertilization consisted of 180 and 250 kg N ha-1 for SS and AW, respectively, plus 200 kg×ha-1 of P2O5, 300 kg×ha-1 of K2O, 50 kg×ha-1 of Ca y 22 kg×ha-1 of Mg. Irrigation was applied by sprinkles and no soil moisture stress occurred at any time in the crop. Samples were periodically taken at two locations, and they consisted of: leaves and shoots, roots, and tuber. We determined dry matter content (DM) and N, P and K uptake. Yield reached 48 t×ha-1 of fresh tuber (12.9 t×ha-1 dry matter) and 32 t×ha-1 of fresh tuber (8.3 t×ha-1 dry matter), for SS and AW, respectively. Total extraction for N, P, and K was 287, 33 and 372 kg×ha-1 for SS, and 227, 24 and 358 kg×ha-1 for AW. To obtain one ton of tuber, the crop required 6.0, 0.7, and 7.8 kg×of N, P and K for SS, and 7.1, 0.75, and 11.2 kg×of N, P and K for AW. We also show the extraction of N, P, and K by component (leaves and shoots, tuber, and root) along the development cycle.