The difficulty of obtaining daily global radiation data has led to the development of models for its estimation, like the Hargreaves equation that uses maximum and minimum temperature weather variables, and the Prescott model, derived from Angström, that requires data such as sunshine hours and Angot value. Artificial neural network models are efficient tools for processing in parallel multiple input variables and estimating non-linear variables with considerable accuracy. The aim of this work was to compare the daily global radiation measured at the Santa Rosa 1 AC weather sta¬tion in irrigation district 075 in los Mochis, Sinaloa State, Mexico, with that estimated by the Hargreaves, calibrated Hargreaves, Angström-Prescott, calibrated Angström-Prescott and the feedforward backpropagation and radial basis function artificial neural network models. The Angström-Prescott model with coefficients a and b calibrated with R2 of 0.82 and RMSE of 2.33, together with the backpropagation algorithm multilayer in 3 scenarios (input variables of Julian day, minimum and maximum temperature, vapour mean pressure, relative humidity, wind speed, sunshine hours, Angot value) with R2 of 0.87 and RMSE of 1.97, were the best estimators of daily global radiation.