Characteristics of pine pitch canker disease are described. The causal agent was Fusarium subglutinans (Deuteronmycotina: Mo-niliales). The fungus was found in northern and central regions of Mexico: Federal District and states of Durango, Hidalgo, Jalisco, Mexico, Michoacán, Morelos, Nuevo León, Puebla, Tamaulipas, Tlaxcala, and Verzcruz. The range of hosts includes 19 species of pine. Trees of different ages were affected by the disease; a great variability in symptoms was observed, from shoot wilting, with no resin flow, to cankers in stems, with heavy resin flow. Spropdochia were found in Pinus douglasiana and P. radiata. Pathogenicity tests were done; 15 strains were inoculated in 12 species of pine. Also, the spread and development of the infection in inoculated pine seedlings were registered. The results showed significant differences in (p00.05%) in pathogenicity. The fungus faster in P. cembroides, P. montezurnae, P. gregii, P. pseudostrobus and P. patula than in P. ayacahuite, P. Ieiophylla, P. douglasiana, P. mi-choacana, P. halepensis, and P. pringlei. The isolated strains from P. pseudostrobus, P. arizonica, P. discolor, and P. leiophylla were more pathogenic than any other strain. Finally, the characteristics of the fungus are presented.