We assessed the effect of the Steiner nutrient solution (NS) at 25, 50, 75 and 100 % of its original concentration, in combination with 4, 6 and 8 plants·m-2, in a completely randomized experimental design, on yield and development of Physalis peruviana L. This research was carried out under greenhouse conditions from June 2010 to July 2011. The ecotype Colombia was cultivated in black plastic bags with tezontle stones and drip irrigation. The following variables were evaluated: fruit yield, number of fruits per plant, weight of fruit with and without husk, and average fruit weight. To determine the crop nutrient uptake leaf sampling were taken in the vegetative (VS) and reproductive stage (RS) and N, P, K, Ca, Mg, Fe, Mn, Zn, and B were quantified. Quality variables were total soluble solids (TSS; °Brix) and pH of the fruit. Significant differences were found for yield variables. The higher yield was obtained with plants supplied with the complete solution plus 8 plants·m-2. The nutrient solution with 75 and 100 % with 4 plants·m-2 obtained the higher individual weight of fruit. During VS the nutrient solution affected the concentration of N, K, Mg, Fe, and B; and the plant density influenced K concentration in leaf. During
RS we found differences in concentration of K, P, Mg, and Mn due to nutrient solution, and Fe was affected by plant density. The TSS and
pH of the fruit did not show significant differences.